Schedule ConsultationTPE Research Index. Clinical evidence and plain-language explainers, compiled by the Avinity Health medical team. All reviews cite primary peer-reviewed sources.
Full Clinical Reference →Therapeutic Plasma Exchange Research
A curated index of clinical evidence, peer-reviewed studies, and plain-language explainers on TPE — compiled by the medical team at Avinity Health.
See How TPE Is Offered at Avinity →Start Here
Three resources, from a comprehensive clinical reference to a plain-language patient guide and a focused review of emerging evidence — each maintained by the Avinity Health medical team.
Therapeutic Plasma Exchange (TPE): Research, Statistics, Costs & Clinical Data
A comprehensive clinical reference synthesizing two decades of published research — from the early parabiosis studies through the AMBAR trial and recent biological-aging work. It covers the procedure's mechanism, ASFA evidence tiers, application areas, candidacy criteria, protocol comparisons, and cost ranges, with full citations to primary sources. The most detailed resource in the index.
Read More →Plasma Exchange Explained in Plain English
A patient-facing guide that explains what therapeutic plasma exchange is, why removing and replacing plasma may produce measurable biological changes, and what the research does and does not yet establish — all without medical jargon. It also walks through the procedure experience, costs, candidacy, and the often-confused distinction between TPE, plasmapheresis, and plasma donation.
Read More →Can Therapeutic Plasma Exchange Reduce Microplastics? What the First Human Study Actually Found
A clinical review of the first peer-reviewed study (Weinstein et al., 2026) to measure whether TPE reduces circulating microplastics in human patients. It explains why the procedure produced a clear reduction only in patients with high baseline levels, how the plastic apheresis equipment itself can add particles at lower levels, and why baseline testing matters before drawing conclusions about benefit.
Read More →The research compiled here reflects the clinical foundation behind PlasmaRestore™, Avinity Health's physician-guided Therapeutic Plasma Exchange program. Our medical team reviews and contextualizes emerging evidence to help patients make informed decisions.
Ready to Learn More?
See how Therapeutic Plasma Exchange is delivered at Avinity Health, or book a consultation with our physician-led team in Scottsdale.