NAD+ levels decline with age and chronic stress. IV delivery restores them directly — bypassing digestion and reaching your cells in a form they can use immediately. Physician-guided, RN-administered at Avinity Health.
Free consultation · No commitment required · Serving Scottsdale, Phoenix & Arizona

The Science
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell of the human body. It plays a central role in energy metabolism — specifically in the conversion of nutrients into ATP, the cellular fuel that powers essentially every biological process. Beyond energy production, NAD+ is involved in DNA repair, circadian rhythm regulation, and the activation of sirtuins, a class of proteins associated with longevity and cellular stress response.
NAD+ levels decline significantly with age — research suggests levels drop by roughly 50% between early adulthood and midlife — and are further depleted by chronic stress, poor sleep, alcohol use, and metabolic dysfunction. This decline is thought to contribute to reduced cellular energy, slower recovery, cognitive changes, and accelerated aging at the cellular level.
IV delivery provides NAD+ directly to the bloodstream. Unlike oral supplementation, which relies on digestive conversion and absorption, IV NAD+ bypasses these steps entirely and is available to cells immediately.
NAD+ is one focused option within our broader IV and injectable therapies in Scottsdale program.
Book a consultation
Who NAD+ IV Therapy Is For
NAD+ IV therapy is appropriate for individuals focused on long-term cellular health — not a quick fix. It is most commonly sought by patients who:
Are experiencing persistent fatigue, reduced mental clarity, or slower recovery that lifestyle changes have not fully resolved
Are pursuing a structured longevity or anti-aging protocol and want cellular-level support
Are in recovery from alcohol dependence or metabolic stress and want to support cellular repair
Are athletes or high-performers focused on mitochondrial function and sustained energy output
Are already receiving other IV therapy in Scottsdale services at Avinity Health and want to add NAD+ as part of a broader optimization plan
How It Works
Your visit begins with a brief review of your health history, current goals, and any relevant medications or conditions. This confirms NAD+ is appropriate and determines the right starting dose.
NAD+ infusion dose and rate are individualized. Your nurse confirms the protocol before the infusion begins. First-time patients typically start at a conservative dose to assess tolerance.
NAD+ is administered via IV over 2 to 4 hours in a comfortable clinical setting. Infusion rate is managed carefully — going too fast can cause transient discomfort, so your nurse monitors and adjusts throughout the session.
Most patients return to normal activity the same day. Some notice effects within hours; others see the most significant changes over the following 24 to 48 hours as cellular processes respond. Ongoing frequency is discussed at the end of your session.
Why Patients Choose Us
| Most IV Clinics | Avinity Health | |
|---|---|---|
| Dose Selection | Patient self-selects from a menu | Dose determined after clinical intake |
| Clinical Oversight | Varies | RN-administered, physician-guided |
| Infusion Rate Management | Standardized rate | Monitored and adjusted by nurse throughout session |
| Integration with Other Services | Single-session focus | Part of a broader health optimization plan if appropriate |
| First-Time Protocol | Same as repeat patients | Conservative starting dose to assess individual tolerance |
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of the body, essential to energy metabolism, DNA repair, and cellular function. IV delivery provides NAD+ directly to the bloodstream, bypassing digestive absorption and allowing the body to utilize it immediately.
NAD+ infusions at Avinity Health typically take 2 to 4 hours depending on the dose and individual tolerance. The timeline is discussed during your intake before treatment begins.
Most patients begin with a series of sessions spaced closely together, then transition to periodic maintenance infusions. The right frequency depends on your goals and how your body responds. Your nurse will recommend an approach based on your intake and initial results.
At Avinity Health, all NAD+ infusions are administered by registered nurses within a physician-guided clinical framework. A brief intake process confirms suitability before treatment. NAD+ is a naturally occurring compound and is generally well tolerated, though infusion rate and dose are managed carefully to minimize any discomfort.
Oral NAD+ precursors like NMN and NR are absorbed through the digestive system, which limits bioavailability and consistency. IV delivery bypasses digestion entirely, delivering NAD+ directly to the bloodstream for immediate cellular uptake. The two approaches are not mutually exclusive and can complement each other.
Service Areas
Avinity Health is located at 11000 N. Scottsdale Road, Suite 100 — accessible from North Scottsdale, Gainey Ranch, Paradise Valley, Kierland, and McCormick Ranch. Patients searching for NAD+ IV therapy near Scottsdale, NAD+ infusion near Paradise Valley, or NAD+ IV drip Scottsdale receive the same physician-guided, clinically grounded approach at every visit.